The Weyland-Yutani Corporation, often shortened to Weyland-Yutani and commonly referred to as Wey-Yu or simply "The Company", is a large British/Japanese multinational conglomerate. It was founded in 2099 by the merger of Weyland Corp and the Yutani Corporation. Weyland-Yutani is primarily a technology supplier, manufacturing synthetics, spaceships and computers for a wide range of industrial and commercial clients, making them a household name. Weyland-Yutani also has numerous non-manufacturing interests; the company has extensive assets in interplanetary shipping and transport, and is one of the corporations that operates human colonies outside the solar system, through the Extrasolar Colonization Administration. The company also has a seat on the review board of the Interstellar Commerce Commission (which it owns, although the organization itself is ostensibly independent). They hold their main offices in Tokyo, London, San Francisco, the Sea of Tranquillity on Luna and on Thedus.

Weyland-Yutani is consistently portrayed as exhibiting the worst aspects of corporate profiteering, willing to sacrifice decency and life in the endless pursuit of monetary profits.